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Yik J.J., Crossley M., Quinlan K.G.R.

2017 Genome Editing of Erythroid Cell Culture Model Systems

Masuda T, Wang X, Maeda M, Canver MC, Sher F, Funnell AP, Fisher C, Suciu M, Martyn GE, Norton LJ, Zhu C, Kurita R, Nakamura Y, Xu J, Higgs DR, Crossley M, Bauer DE, Orkin SH, Kharchenko PV, Maeda T

2016 Transcription factors LRF and BCL11A independently repress expression of fetal hemoglobin. Science. 2016 Jan 15;351(6270):285-9. doi: 10.1126/science.aad3312. PMID: 26816381

Knights AJ, Yik JJ, Jusoh HM, Norton LJ, Funnell AP, Pearson RC, Bell-Anderson KS, Crossley M, Quinlan KG.

2016 Krüppel-like factor 3 (KLF3/BKLF) is required for widespread repression of the inflammatory modulator galectin-3 (Lgals3). J Biol Chem. 2016 May 24. pii: jbc.M116.715748. [Epub ahead of print] PMID: 27226561

Martyn GEQuinlan KGCrossley M.

2016 The regulation of human globin promoters by CCAAT box elements and the recruitment of NF-Y

Wienert B, Funnell AP, Norton LJ, Pearson RC, Wilkinson-White LE, Lester K, Vadolas J, Porteus MH, Matthews JM, Quinlan KG, Crossley M.

2015 Editing the genome to introduce a beneficial naturally occurring mutation associated with increased fetal globin. Nat Commun. 2015 May 14;6:7085. doi: 10.1038/ncomms8085.

Lim WF, Burdach J, Funnell AP, Pearson RC, Quinlan KG, Crossley M.

2015 Directing an artificial zinc finger protein to new targets by fusion to a non-DNA-binding domain. Lim WF, Burdach J, Funnell AP, Pearson RC, Quinlan KG, Crossley M. Nucleic Acids Res. 2015 Dec 15. pii: gkv1380. [Epub ahead of print]

Dewi V, Kwok A, Lee S, Lee MM, Tan YM, Nicholas HR, Isono KI, Weinert B, Mak KS, Knights AJ, Quinlan KG, Cordwell SJ, Funnell AP, Pearson RC, Crossley M.

2015 Phosphorylation of Kruppel-like Factor 3 (KLF3/BKLF) and C-terminal Binding Protein 2 (CtBP2) by Homeodomain Interacting Protein Kinase 2 (HIPK2) Modulates KLF3 DNA Binding and Activity. J Biol Chem. 2015 Feb 6. pii: jbc.M115.638338.

Burdach J, Funnell AP, Mak KS, Artuz CM, Wienert B, Lim WF, Tan LY, Pearson RC, Crossley M.

2014 Regions outside the DNA-binding domain are critical for proper in vivo specificity of an archetypal zinc finger transcription factor. Nucleic Acids Res. 2014 Jan;42(1):276-89. doi: 10.1093/nar/gkt895. Epub 2013 Oct 7.

Funnell AP, Crossley M.

2014 Hemophilia B Leyden and once mysterious cis-regulatory mutations. Trends Genet. 2014 Jan;30(1):18-23. doi: 10.1016/j.tig.2013.09.007. Epub 2013 Oct 16. Review.

Knights AJ, Funnell AP, Pearson RC, Crossley M, Bell-Anderson KS.

2014 Adipokines and insulin action: A sensitive issue. Adipocyte. 2014 Apr 1;3(2):88-96. doi: 10.4161/adip.27552. Epub 2014 Jan 8. Review.

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