Martyn, G. E., Wienert, B., Kurita, R., Nakamura, Y., Quinlan, K. G., & Crossley, M.
|
2019 |
A natural regulatory mutation in the proximal promoter elevates fetal globin expression by creating a de novo GATA1 site |
Blood |
Shah, M., Funnell, A.P., Quinlan, K.G. and Crossley, M.
|
2019 |
Hit and Run Transcriptional Repressors Are Difficult to Catch in the Act |
PubMed |
Martyn, G.E., Wienert, B., Yang, L., Shah, M., Norton, L.J., Burdach, J., Kurita, R., Nakamura, Y., Pearson, R.C.M., Funnell, A.P.W., Quinlan, K.G.R. and Crossley, M.
|
2018 |
Natural regulatory mutations elevate the fetal globin gene via disruption of BCL11A or ZBTB7A binding |
Nature Genetics |
Knights AJ, Vohralik EJ, Hoehn KL, Crossley M, Quinlan KGR
|
2018 |
Defining Eosinophil Function in Adiposity and Weight Loss |
PubMed |
Wienert B, Martyn GE, Funnell APW, Quinlan KGR, Crossley M.
|
2018 |
Wake-up Sleepy Gene: Reactivating Fetal Globin for β-Hemoglobinopathies |
PubMed |
Artuz CM, Knights AJ, Funnell APW, Gonda TJ, Ravid K, Pearson RCM, Quinlan KGR, Crossley M.
|
2018 |
Partial reprogramming of heterologous cells by defined factors to generate megakaryocyte lineage-restricted biomolecules |
Biotechnology Reports |
Norton, L. J., Funnell, A. P., Burdach, J., Wienert, B., Kurita, R., Nakamura, Y., Philipsen, S., Pearson, R. C., Quinlan, K. G., & Crossley, M.
|
2017 |
KLF1 directly activates expression of the novel fetal globin repressor ZBTB7A/LRF in erythroid cells |
Blood Advances |
Norton, L. J., Hallal, S., Stout, E. S., Funnell, A. P. W., Pearson, R. C. M., Crossley, M., & Quinlan, K. G. R.
|
2017 |
Direct competition between DNA binding factors highlights the role of Krüppel-like Factor 1 in the erythroid/megakaryocyte switch |
Scientific Reports |
Wienert, B., Martyn, G. E., Kurita, R., Nakamura, Y., Quinlan, K. G. R., & Crossley, M.
|
2017 |
KLF1 drives the expression of fetal hemoglobin in British HPFH |
Blood |
Hamey, J.J., Wienert, B., Quinlan, K.G. and Wilkins, M.R.
|
2017 |
METTL21B is a novel human lysine methyltransferase of translation elongation factor 1A: discovery by CRISPR/Cas9 knock out |
PubMed |