Publications

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Martyn GEQuinlan KGCrossley M.

2016 The regulation of human globin promoters by CCAAT box elements and the recruitment of NF-Y

Knights AJ, Yik JJ, Jusoh HM, Norton LJ, Funnell AP, Pearson RC, Bell-Anderson KS, Crossley M, Quinlan KG.

2016 Krüppel-like factor 3 (KLF3/BKLF) is required for widespread repression of the inflammatory modulator galectin-3 (Lgals3). J Biol Chem. 2016 May 24. pii: jbc.M116.715748. [Epub ahead of print] PMID: 27226561

Masuda T, Wang X, Maeda M, Canver MC, Sher F, Funnell AP, Fisher C, Suciu M, Martyn GE, Norton LJ, Zhu C, Kurita R, Nakamura Y, Xu J, Higgs DR, Crossley M, Bauer DE, Orkin SH, Kharchenko PV, Maeda T

2016 Transcription factors LRF and BCL11A independently repress expression of fetal hemoglobin. Science. 2016 Jan 15;351(6270):285-9. doi: 10.1126/science.aad3312. PMID: 26816381

Lim WF, Burdach J, Funnell AP, Pearson RC, Quinlan KG, Crossley M.

2015 Directing an artificial zinc finger protein to new targets by fusion to a non-DNA-binding domain. Lim WF, Burdach J, Funnell AP, Pearson RC, Quinlan KG, Crossley M. Nucleic Acids Res. 2015 Dec 15. pii: gkv1380. [Epub ahead of print]

Wienert B, Funnell AP, Norton LJ, Pearson RC, Wilkinson-White LE, Lester K, Vadolas J, Porteus MH, Matthews JM, Quinlan KG, Crossley M.

2015 Editing the genome to introduce a beneficial naturally occurring mutation associated with increased fetal globin. Nat Commun. 2015 May 14;6:7085. doi: 10.1038/ncomms8085.

Dewi V, Kwok A, Lee S, Lee MM, Tan YM, Nicholas HR, Isono KI, Weinert B, Mak KS, Knights AJ, Quinlan KG, Cordwell SJ, Funnell AP, Pearson RC, Crossley M.

2015 Phosphorylation of Kruppel-like Factor 3 (KLF3/BKLF) and C-terminal Binding Protein 2 (CtBP2) by Homeodomain Interacting Protein Kinase 2 (HIPK2) Modulates KLF3 DNA Binding and Activity. J Biol Chem. 2015 Feb 6. pii: jbc.M115.638338.

Yücel D, Hoe M, Llamosas E, Kant S, Jamieson C, Young PA, Crossley M, Nicholas HR.

2014 SUMV-1 antagonizes the activity of synthetic multivulva genes in Caenorhabditis elegans. Dev Biol. 2014 Aug 15;392(2):266-82. doi: 10.1016/j.ydbio.2014.05.018. Epub 2014 Jun 2.

Ballester B, Medina-Rivera A, Schmidt D, Gonzàlez-Porta M, Carlucci M, Chen X, Chessman K, Faure AJ, Funnell AP, Goncalves A, Kutter C, Lukk M, Menon S, McLaren WM, Stefflova K, Watt S, Weirauch MT, Crossley M, Marioni JC, Odom DT, Flicek P, Wilson MD.

2014 Multi-species, multi-transcription factor binding highlights conserved control of tissue-specific biological pathways. Elife. 2014 Oct 3;3. doi: 10.7554/eLife.02626.

Clifton MK, Westman BJ, Thong SY, O'Connell MR, Webster MW, Shepherd NE, Quinlan KG, Crossley M, Blobel GA, Mackay JP.

2014 The identification and structure of an N-terminal PR domain show that FOG1 is a member of the PRDM family of proteins. PLoS One. 2014 Aug 27;9(8):e106011. doi: 10.1371/journal.pone.0106011. eCollection 2014.

Mak KS, Burdach J, Norton LJ, Pearson RC, Crossley M, Funnell AP.

2014 Repression of chimeric transcripts emanating from endogenous retrotransposons by a sequence-specific transcription factor. Genome Biol. 2014 Apr 30;15(4):R58. doi: 10.1186/gb-2014-15-4-r58.

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